Understanding how genetics affect the development and progression of particular diseases as well as forecasting an individual's response to different therapy requires an understanding of chromosomes, or cytogenetics. It is anticipated to be essential to the advancement of the fields of personalized medicine and drug development. It is now a crucial tool for the diagnosis of cancer.When chromosome structure was first defined and the relationship between defects and disease was explained, the term "cytogenetics" first became widely used. Chromosome abnormalities such as damaged, deleted, extra, or rearranged chromosomes can be identified by cytogenetic examination of blood, tissue, or bone marrow samples. Since the term "cytogenetics" was originally employed, its meaning has evolved.
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